High Doses of Caffeine during the Peripubertal Period in the Rat Impair the Growth and Function of the Testis

Table 1

Histomorphometric parameters analyzed in the testes of the control and caffeine-fed groups.

Parameter	CTRL ()	CF1 ()	CF2 ()
Seminiferous tubule diameter (μm)	295.6 ± 14.03	280.1 ± 9.05	271.8 ± 11.58
Germinal epithelium height (μm)	167.3 ± 6.77	163.8 ± 7.15	153.6 ± 8.2
Seminiferous tubule number	60 ± 4.6	61 ± 2.8	63 ± 6.5
Intertubular area (mm^2)	0.07 ± 0.02	0.10 ± 0.03	0.11 ± 0.01

Values are expressed as mean ± SD. , versus CTRL; ^† CF1 versus CF2. CTRL: control; CF1: caffeine 120 mg/kg/day; CF2: caffeine 180 mg/kg/day.