Research Article

Altered Daytime Fluctuation Pattern of Plasminogen Activator Inhibitor 1 in Type 2 Diabetes Patients with Coronary Artery Disease: A Strong Association with Persistently Elevated Plasma Insulin, Increased Insulin Resistance, and Abdominal Obesity

Table 3

The variable independently related to altered daytime fluctuation pattern of PAI-1 in multiple stepwise linear regression analyses.

(95% CI)Adjusted value

(1) WHR−89.05 (−162.54 to −15.56)−0.3570.1670.1450.019
(2) AUC of insulin−0.04 (−0.07 to −0.02)−0.3100.2610.2200.040

Dependent variable in the model: percentage of PAI-1 decrease during the day.
Independent variable in the model: HOMA-IR, AUC of plasma insulin, AUC of plasma glucose, LDL-chol, HDL-chol, triglycerides, BMI, and WHR (adjusted for age, gender, and presence of diabetes).