Expression of Intratumoral IGF-II Is Regulated by the Gene Imprinting Status in Triple Negative Breast Cancer from Vietnamese Patients

Figure 1

3% agarose gel showing ApaI restriction digestion of the 292 gDNA PCR products for the 48 breast normal (N) and malignant (M) samples. The IGF-II allelic pattern determined to be Heterozygous (Het; ) displayed three bands of 292, 227, and 65 bp. The Homozygous with SNP (Hom SNP; ) allelic pattern displayed two bands of 227 and 65 bp. Only one band (292 bp) is seen in the Homozygous without a SNP (Hom; ) IGF-II allelic pattern. Symbols , , $, , and represent paired samples from normal and malignant that were not next to each other’s lane.