Vitamin D Status and VDR Genotype in NF1 Patients: A Case-Control Study from Southern Brazil

Table 1

Clinical and demographic features of NF1 patients and controls included in the study.

Features	NF1 patients ()		Controls ()		value
	(%)	Media/range; (years)	(%)	Media/range; (years)
Gender; Female	31 (68.9)		33 (73.3)		0.646^3
Age		38.6/18 to 72		36.7/18.6 to 58.6	0.212^5
Skin type (Fitzpatrick)					0.129^4
1	1 (2.2)		0
2	8 (17.8)		12 (26.7)
3	13 (28.9)		19 (42.2)
4	5 (11.1)		7 (15.6)
5	14 (31.1)		5 (11.1)
6	4 (8.9)		2 (4.4)
Habit of smoking	6 (13.3)		8 (17.8)		0.722^3
Use of alcohol^1	26 (57.8)		21 (46.7)		0.297^3
No sun avoidance	39 (86.7)		35 (77.8)		0.275^3
Previous cancer diagnosis	5 (11.1)		0 (0.0)		0.021^3
Short stature^2	11 (25.5)		3 (6.8)		0.011^3

Socially; ²according to the World Health Organization () for controls and to Neurofibromatosis 1 Growth Charts for the cases; ³Fisher’s exact test; ⁴chi-square test; ⁵Student’s -test.
Breast cancer (); Hurthle cell adenoma (); schwannoma (); Hodgkin lymphoma (); optic pathway glioma ().