Research Article
The Warthin-Like Variant of Papillary Thyroid Carcinoma: A Comparison with Classic Type in the Patients with Coexisting Hashimoto’s Thyroiditis
Table 3
Comparison of clinicopathologic characteristics between WLPTC and classic PTC coexisting with HT.
| Characteristic | Classic PTC with HT () | WLPTC () | value |
| Mean age (years) | 46 (25–73) | 46 (18–77) | 0.892 | Age | | | 0.833 | <45 | 21 (40%) | 17 (43%) | | ≥45 | 32 (60%) | 23 (58%) | | Sex | | | 0.081 | Female | 52 (98%) | 35 (88%) | | Male | 1 (2%) | 5 (13%) | | Multifocality | | | 0.207 | Unifocal | 25 (47%) | 25 (63%) | | Multifocal | 28 (53%) | 15 (38%) | | Surgery type | | | 0.611 | Lobectomy | 12 (23%) | 7 (18%) | | Total thyroidectomy | 41 (77%) | 33 (83%) | | Median tumor size (cm) | 0.7 (0.3–4.5) | 1.0 (0.4–2.2) | 0.285 | pT stage | | | 0.467 | pT1 | 34 (64%) | 30 (75%) | | pT2 | 1 (2%) | 1 (3%) | | pT3 | 18 (34%) | 9 (23%) | | Extrathyroidal extension | | | 0.257 | Absent | 35 (66%) | 31 (78%) | | Present | 18 (34%) | 9 (23%) | | pN stage | | | 0.833 | pN0 | 31 (59%) | 22 (55%) | | pN1 | 22 (42%) | 18 (45%) | | Preoperative diagnosis | | | 0.675 | Atypia of undetermined significance | 2 (4%) | 2 (5%) | | Suspicious for PTC | 13 (25%) | 7 (18%) | | PTC | 38 (72%) | 31 (78%) | | BRAF mutation | | | 0.494 | Absent | 14 (26%) | 14 (35%) | | Present | 39 (74%) | 26 (65%) | |
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PTC, papillary thyroid carcinoma; WLPTC, Warthin-like variant of papillary thyroid carcinoma; HT, Hashimoto’s thyroiditis.
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