Research Article
The Clinicopathological Features of BRAF Mutated Papillary Thyroid Cancers in Chinese Patients
Table 2
Relationship between the BRAFV600E mutation and clinicopathological factors in PTC.
| | | Total, (%) | BRAFV600E mutation, (%) | | value | | | Mutation () | Wild () |
| | Gender | | | | 2.288 | 0.130 | | Female | 409 (75.3) | 121 (29.6) | 288 (70.4) | | | | Male | 134 (24.7) | 49 (36.6) | 85 (63.4) | | | | Age at diagnosis | | | | 0.234 | 0.629 | | <45 | 219 (40.3) | 66 (30.1) | 153 (69.9) | | | | ≥45 | 324 (59.7) | 104 (32.1) | 220 (69.7) | | | | Multifocality | | | | 0.314 | 0.575 | | No | 313 (57.6) | 95 (30.4) | 218 (69.6) | | | | Yes | 230 (42.4) | 75 (32.6) | 155 (67.4) | | | | Bilaterality | | | | 4.703 | 0.030 | | No | 418 (77.0) | 121 (28.9) | 297 (71.1) | | | | Yes | 125 (23.0) | 49 (39.2) | 76 (60.8) | | | | Tumor size (cm) | | | | 31.109 | <0.001 | | ≤1 | 345 (63.5) | 79 (22.9) | 266 (77.1) | | | | >1 | 198 (36.5) | 91 (46.0) | 107 (54.0) | | | | Extrathyroidal invasion | | | | 23.142 | <0.001 | | No | 184 (33.9) | 33 (17.9) | 151 (82.1) | | | | Yes | 359 (66.1) | 137 (38.2) | 222 (61.8) | | | | LNM | | | | 7.452 | 0.006 | | No | 222 (40.9) | 55 (24.8) | 167 (75.2) | | | | Yes | 321 (59.1) | 115 (35.8) | 206 (64.2) | | | | AJCC stage | | | | 6.741 | 0.072 | | I | 434 (79.9) | 132 (30.4) | 302 (69.6) | | | | II | 6 (1.1) | 2 (33.3) | 4 (66.7) | | | | III | 70 (12.9) | 19 (27.1) | 51 (72.9) | | | | IV | 33 (6.1) | 17 (51.5) | 16 (48.5) | | |
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