International Journal of Endocrinology

Research Article

The Relationship between Serum Ferritin and Insulin Resistance in Different Glucose Metabolism in Nonobese Han Adults

Table 1

Clinical and laboratory characteristics of the subjects in different groups.


Variable	NGT	IGR	DM
Variable	= 32	= 33	= 31

BMI (kg/m²)	22.7 ± 1.2	23.1 ± 1.1	23.2 ± 1.1	1.186	0.232
WC (cm)	77.4 ± 6.7	82.5 ± 5.6^▲	83.3 ± 7.7^▲	5.020	0.009
SBP (mmhg)	118.2 ± 14.4	124.9 ± 18.2	140.0 ± 27.9^▲■	6.164	0.004
DBP (mmhg)	76.4 ± 10.4	77.4 ± 9.4	89.3 ± 10.4^▲■	10.918	0.000
FPG (mmol/L)	5.3 ± 0.2	6.0 ± 0.5^▲	7.6 ± 0.6^▲■	137.08	0.000
OGTT, 2 hPG	6.3 ± 0.3	8.2 ± 0.6^▲	11.3 ± 0.6^▲■	161.11	0.000
FTI (μIU/mL) (IQR)	7.8 ± 3.6	11.6 ± 4.9^▲	8.3 ± 3.7^■	5.714	0.005
OGTT, 2 h insulin (IQR)	43.6 ± 6.6	32.2 ± 4.1^▲	28.7 ± 4.6^▲	19.724	0.000
TG (mmol/L) (IQR)	1.1 (0.5, 1.5)	1.0 (0.6, 3.9)^▲	1.3 (0.5, 3.1)^▲■	16.78	0.000
HDL-C (mmol/L)	1.5 ± 0.2	1.5 ± 0.4	1.1 ± 0.2^▲■	13.907	0.000
HOMA-IR (IQR)	2.4 ± 0.8	3.3 ± 1.1^▲	4.9 ± 2.6^▲■	17.324	0.000
HOMA-β (IQR)	121.3 ± 36.7	97.2 ± 42.3^▲	89.6 ± 46.4^▲	2.861	0.048
SF (μg/mL) (IQR)	1.8 ± 0.2	2.0 ± 0.3^▲	2.2 ± 0.2^▲■	14.55	0.000

Values are expressed as mean (SD), and when not normally distributed, they were ln-transformed for analysis and are expressed as medians (IQR). SD: standard deviation; IQR: interquartile range. Comparisons were done between the three groups using analysis of variance (ANOVA) and Kruskal-Wallis. If there was statistically significant, multiple comparisons were made by least significant difference (LSD) test. Group NGT consisted of 32 normal glucose tolerant subjects; group IGR consisted of 33 impaired glucose tolerant and/or impaired fasting glucose subjects; group DM consisted of 31 newly diagnosed diabetes mellitus subjects. BMI: body mass index; WC: waist circumference; SBP: systolic blood pressure; DBP: diastolic blood pressure; SF: serum ferritin; FPG: fasting plasma glucose; OGTT: oral glucose tolerance test; 2 hPG: 2 h plasma glucose; FTI: fasting true insulin; TG: triglycerides; HDL-C: high density lipoprotein cholesterol; HOMA: homeostasis model assessment; HOMA-IR: homeostasis model assessment of insulin resistance; HOMA-β: homeostasis model assessment of beta cell function. ^▲Compared with group NGT , ^■compared with group IGR .