Research Article

The Associations of Novel Vitamin D3 Metabolic Gene CYP27A1 Polymorphism, Adiponectin/Leptin Ratio, and Metabolic Syndrome in Middle-Aged Taiwanese Males

Table 2

Means ± standard deviations or numbers (%) of the MetS parameters in the patients with the CYP27A1 rs4674344 SNP.

Subjects with AA ()Subjects with T-carrier () value of the association with CYP27A1 rs4674344

MetS, (%)0.038*
 Yes 158 (35.4)90 (44.6)
 No289 (64.6)112 (55.4)
 Component numbers:
  0 ()78 (17.8)21 (10.4)
  1 ()113 (25.5)58 (28.7)
  2 ()96 (21.6)33 (16.3)
  3 ()90 (20.2)52 (25.7)
  4 ()53 (11.9)30 (14.9)
  5 ()15 (3.3)8 (4.0)
Number of MetS criteria1.9 ± 1.42.1 ± 1.40.038*
Individual MetS Component, (%)
 High waist circumference118 (26.3)65 (32.1)0.26
 High blood pressure273 (61.1)127 (62.9)0.38
 Low HDL95 (21.2)55 (27.2)0.25
 High triglyceride150 (33.6)85 (42.1)0.06
 High fasting glucose160 (35.8)79 (39.1)0.51

MetS: metabolic syndrome; HDL: high density lipoprotein. values were adjusted for age, alcohol, smoking, and betel chewing. Significant difference ().