Thyroid Function, Prevalent Coronary Heart Disease, and Severity of Coronary Atherosclerosis in Patients Undergoing Coronary Angiography

Table 2

Characteristics of the study population by thyroid function categories.

Variables	Hyperthyroidism	Euthyroidism	Subclinical hypothyroidism	Overt hypothyroidism
	( = 13)	( = 1589)	( = 165)	( = 32)
Male (%)	53.85	76.84	71.52	34.38
Age (years)	60.92 ± 3.05	62.34 ± 0.25	65.42 ± 0.74	66.81 ± 1.94
Free T4 (pmol/L)	29.06 ± 5.14	15.44 ± 0.05	14.77 ± 0.14	10.45 ± 0.32
TSH (uIU/mL)	0.06 ± 0.02	1.95 ± 0.02	6.24 ± 0.26	14.39 ± 2.94
Coronary heart disease (%)	76.92	77.34	83.03	84.37
Gensini score	32.27 ± 9.41	37.95 ± 1.09	40.44 ± 3.84	56.61 ± 8.26
BMI (Kg/m^2)	23.89 ± 0.78	24.78 ± 0.08	24.70 ± 0.24	25.57 ± 0.57
Diabetes (%)	53.85	33.86	36.36	46.88
FPG (mmol/L)	5.66 ± 0.49	5.70 ± 0.04	5.68 ± 0.11	6.13 ± 0.33
2-h PPG (mmol/L)	9.71 ± 1.02	9.20 ± 0.10	9.18 ± 0.30	9.97 ± 0.85
HbA1c (%)	6.46 ± 0.32	6.19 ± 0.03	6.05 ± 0.07	6.47 ± 0.20
Hypertension (%)	84.62	69.23	72.12	68.75
SBP (mmHg)	132.83 ± 3.31	129.04 ± 0.35	128.85 ± 1.03	128.45 ± 2.69
DBP (mmHg)	81.67 ± 2.87	77.48 ± 0.21	77.16 ± 0.70	77.32 ± 1.67
Total cholesterol (mmol/L)	3.39 ± 0.22	3.92 ± 0.02	4.00 ± 0.08	4.23 ± 0.21
Triglyceride (mmol/L)	1.44 ± 0.14	1.79 ± 0.04	1.73 ± 0.11	1.92 ± 0.26
LDL-C (mmol/L)	1.65 ± 0.15	2.00 ± 0.02	2.07 ± 0.06	2.13 ± 0.18
HDL-C (mmol/L)	1.08 ± 0.08	1.15 ± 0.01	1.20 ± 0.03	1.31 ± 0.08
Statin use (%)	53.85	51.23	46.06	43.75
Smoking states
Nonsmokers (%)	53.85	47.48	66.67	84.38
Ex-smokers (%)	7.69	8.20	6.67	3.13
Current smokers (%)	38.46	44.33	26.67	12.50

for comparison with euthyroid category.
FPG: fasting plasma glucose; 2-h PPG: 2-hour postprandial plasma glucose; HbA1c: glycosylated hemoglobin; SBP: systolic blood pressure; DBP: diastolic blood pressure; LDL-C: low density lipoprotein cholesterol; HDL-C: high density lipoprotein cholesterol; TSH: thyroid stimulating hormone.