Percutaneous Ethanol Sclerotherapy of Symptomatic Nodules Is Effective and Safe in Pregnant Women: A Study of 13 Patients with an Average Follow-Up of 6.8 Years
Table 2
The effect of PEI therapy on pressure symptom, nodule volume, and TSH-level1.
Number
Type of nodule
Age (ys)
Follow-up (ys)
Total amount of ethanol, mL (% of pretreatment volume)
Degree of pressure symptoms2
Size of nodule, mL (% of pretreatment volume)
TSH (mIU/L)
Final result of one series of PEI
Before therapy
On last visit before delivery
On final visit
Before therapy
On last visit before delivery
On final visit
Before therapy
On last visit before delivery
On final visit
1.
Nontoxic, cystic
22
12
10.8 (60.3)
2
1
0
17.9
3 (16.7)
1.8 (10.1)
1.01
1.20
1.04
Success
2.
Nontoxic, cystic
25
2
10.7 (43.0)
3
0
0
24.9
15.3 (61.4)
17.2 (69.1)
0.87
1.11
2.91
No success
3.
Nontoxic, cystic
29
9
21.5 (70.3)
3
0
1
30.6
8.1 (26.5)
6.9 (22.5)
3.01
2.58
2.73
Success
4.
Nontoxic, cystic
34
16
4.6 (53.5)
2
0
0
8.6
2.2 (25.6)
0.7 (8.1)
0.33
0.76
0.69
Success
5.
Nontoxic, cystic
39
2
6.8 (57.1)
3
1
3
11.9
2.6 (21.8)
11.7 (98.3)
2.39
1.99
1.54
No success
6.
Nontoxic, cystic
43
2
18.4 (74.5)
3
1
1
24.7
9.0 (36.4)
7.2 (29.1)
1.52
1.43
1.47
Success
7.
Nontoxic, solid
30
7
8.4 (83.2)
2
0
1
10.1
4.7 (46.5)
7.9 (78.2)
2.76
2.26
2.31
No success
8.
Nontoxic, solid
32
10
5.5 (61.8)
1
0
0
8.9
3.6 (40.4)
6.1 (68.5)
0.97
1.34
1.13
No success
9.
Nontoxic, solid
35
3
9.7 (71.9)
3
0
0
13.5
5.1 (37.8)
5.1 (37.8)
1.62
1.16
1.25
Success
10.
Nontoxic, solid
37
8
15.5 (70.8)
1
1
2
21.9
10.4 (47.5)
15.5 (70.8)
2.11
2.02
2.79
No success
11.
Toxic
20
2
8.9 (64.5)
1
0
0
13.8
5.7 (41.3)
6.4 (46.4)
0
0.03
0.001
No success
12.
Toxic
31
11
6.2 (77.5)
0
0
0
8.0
3.1 (38.8)
3.9 (48.8)
03
0.91
1.10
Success
13.
Toxic
39
5
3.9 (90.7)
0
0
0
4.3
1.2 (27.9)
0.9 (20.9)
2.913
0.45
0.8
Success
Mean ± SD
32 6,86
6.84 4.61
10.1 (67.6) 5.40 (12.8)
1.84 1.14
0.31 0.48
0.62 0.96
15.3 8.0
5.68 (36.0) 4.01 (12.2)
7.02 (46.8) 5.14 (28.4)
1.664 0.89
1.594 0.59
1.794 0.82
The results of one series of PEI are given in this table even in those patients who get a 2nd series of PEI. 2Degree of pressure symptom: 0: none; 1: occasionally in supine position; 2: continuous in supine position; 3: even in upstanding position. 3On propylthiouracil therapy. 4The mean TSH-levels were calculated only in the case of nontoxic nodules.