Clinical Study

Percutaneous Ethanol Sclerotherapy of Symptomatic Nodules Is Effective and Safe in Pregnant Women: A Study of 13 Patients with an Average Follow-Up of 6.8 Years

Table 2

The effect of PEI therapy on pressure symptom, nodule volume, and TSH-level1.

Number Type of noduleAge (ys)Follow-up (ys)Total amount of ethanol, mL (% of pretreatment volume)Degree of pressure symptoms2Size of nodule, mL (% of pretreatment volume)TSH (mIU/L)Final result of one series of PEI
Before therapyOn last visit before deliveryOn final visitBefore therapy On last visit before deliveryOn final visitBefore therapyOn last visit before deliveryOn final visit

1.Nontoxic, cystic221210.8 (60.3)21017.93 (16.7)1.8 (10.1)1.011.201.04Success

2.Nontoxic, cystic 25210.7 (43.0)30024.915.3 (61.4)17.2 (69.1)0.871.112.91No success

3.Nontoxic, cystic29921.5 (70.3)30130.68.1 (26.5)6.9 (22.5)3.012.582.73Success

4.Nontoxic, cystic34164.6 (53.5)2008.62.2 (25.6)0.7 (8.1)0.330.760.69Success

5.Nontoxic, cystic3926.8 (57.1)31311.92.6 (21.8)11.7 (98.3)2.391.991.54No success

6.Nontoxic, cystic43218.4 (74.5)31124.79.0 (36.4)7.2 (29.1)1.521.431.47Success

7.Nontoxic, solid3078.4 (83.2)20110.14.7 (46.5)7.9 (78.2)2.762.262.31No success

8.Nontoxic, solid32105.5 (61.8)1008.93.6 (40.4)6.1 (68.5)0.971.341.13No success

9.Nontoxic, solid3539.7 (71.9)30013.55.1 (37.8)5.1 (37.8)1.621.161.25Success

10.Nontoxic, solid37815.5 (70.8)11221.910.4 (47.5)15.5 (70.8)2.112.022.79No success

11.Toxic2028.9 (64.5)10013.85.7 (41.3)6.4 (46.4)00.030.001No success

12.Toxic31116.2 (77.5)0008.03.1 (38.8)3.9 (48.8)030.911.10Success

13.Toxic3953.9 (90.7)0004.31.2 (27.9)0.9 (20.9)2.9130.450.8Success

Mean ± SD32
6,86
6.84
4.61
10.1 (67.6)
5.40 (12.8)
1.84
1.14
0.31
0.48
0.62
0.96
15.3
8.0
5.68 (36.0)
4.01 (12.2)
7.02 (46.8)
5.14 (28.4)
1.664
0.89
1.594
0.59
1.794
0.82

The results of one series of PEI are given in this table even in those patients who get a 2nd series of PEI.
2Degree of pressure symptom: 0: none; 1: occasionally in supine position; 2: continuous in supine position; 3: even in upstanding position.
3On propylthiouracil therapy.
4The mean TSH-levels were calculated only in the case of nontoxic nodules.