International Journal of Endocrinology / 2015 / Article / Tab 2 / Research Article
Predictors of Subclinical Cardiovascular Disease in Women with Polycystic Ovary Syndrome: Interrelationship of Dyslipidemia and Arterial Blood Pressure Table 2 Clinical and biochemical parameters in women with PCOS and controls related to age.
Parameter Age <30 years ( ) Age ≥30 years ( )
PCOS <30 years versus PCOS ≥30 years
Controls <30 years versus controls ≥30 years value PCOS ( ) Controls ( ) valuePCOS ( ) Controls ( ) value value value adjusted for BMIBMI (kg/m2 ) 23.32 ± 4.94 24.10 ± 6.65 0.507 30.2 ± 7.6 25.69 ± 6.86 0.059 <0.001 / 0.437 WHR 0.82 ± 0.11 0.79 ± 0.07 0.209 0.89 ± 0.09 0.81 ± 0.07 0.006 0.008 0.558 0.442 SBP (mmHg) 116.97 ± 9.14 117.66 ± 11.84 0.744 127.68 ± 13.62 117.5 ± 12.16 0.016 <0.001 0.003 0.965 DBP (mmHg) 75.28 ± 8.17 75.31 ± 9.67 0.986 84.11 ± 10.31 76.94 ± 8.93 0.023 <0.001 0.003 0.559 TC (mmol/L) 4.94 ± 9.60 4.84 ± 0.89 0.597 5.46 ± 1.07 5.23 ± 1.24 0.523 0.028 0.235 0.204 HDL-C (mmol/L) 1.40 ± 0.34 1.36 ± 0.26 0.493 1.23 ± 0.27 1.4 ± 0.32 0.076 0.028 0.669 0.608 LDL-C (mmol/L) 3.07 ± 0.82 2.97 ± 0.69 0.555 3.49 ± 0.99 3.39 ± 1.23 0.770 0.045 0.294 0.128 TG (mmol/L) 1.04 ± 0.52 1.13 ± 0.82 0.604 1.71 ± 1.06 0.98 ± 0.45 0.009 <0.001 0.050 0.483 Glucose (mmol/L) 4.64 ± 0.47 4.62 ± 0.37 0.793 4.87 ± 0.61 4.61 ± 0.51 0.145 0.056 0.337 0.936 Insulin (mU/L) 15.83 ± 8.87 14.73 ± 7.55 0.545 17.96 ± 11.71 19.08 ± 11.16 0.765 0.348 0.028 0.117 HOMA 3.30 ± 1.99 3.0 ± 1.49 0.451 3.96 ± 3.02 3.89 ± 2.37 0.942 0.331 0.080 0.183 Apo-A1 (g/L) 1.61 ± 0.33 1.68 ± 0.36 0.329 1.51 ± 0.25 1.54 ± 0.22 0.706 0.202 0.790 0.145 Apo-B (g/L) 0.87 ± 0.29 0.82 ± 0.22 0.383 1.04 ± 0.27 0.95 ± 0.31 0.354 0.014 0.490 0.074 TC/HDL-C 3.69 ± 1.10 3.68 ± 0.99 0.947 4.57 ± 1.09 3.96 ± 1.54 0.140 0.001 0.329 0.435 TG/HDL-C 0.84 ± 0.59 0.93 ± 0.86 0.520 1.51 ± 1.10 0.77 ± 0.49 0.012 <0.001 0.137 0.470 Testosterone (nmol/L) 2.56 ± 0.95 1.70 ± 0.60 <0.001 2.99 ± 1.05 1.53 ± 0.61 <0.001 0.061 0.158 0.348 SHBG (nmol/L) 39.19 ± 20.94 53.18 ± 27.19 0.012 37.03 ± 29.63 60.06 ± 39.65 0.037 0.693 0.167 0.472 FAI 9.76 ± 10.95 4.20 ± 2.68 <0.001 11.39 ± 7.55 3.92 ± 3.07 <0.001 0.499 0.043 0.735 Androstenedione (ng/mL) 3.38 ± 1.27 2.27 ± 1.18 <0.001 3.44 ± 1.67 1.9 ± 0.95 0.03 0.862 0.964 0.302 DHEAS (nmol/L) 8.46 ± 4.18 6.03 ± 3.08 0.004 7.16 ± 3.29 4.12 ± 2.20 0.002 0.175 0.082 0.025
BMI: body mass index; WHR, waist-to-hip ratio; SBP: systolic blood pressure; DBP: diastolic blood pressure; TC; HDL-C: high-density lipoprotein; LDL-C: low-density lipoprotein; TG: triglycerides; HOMA: homeostatic model assessment; Apo-A1: apolipoprotein A1; Apo-B: apolipoprotein B; DHEAS: dehydroepiandrosterone sulfate; SHBG: sex-hormone-binding globulin; FAI: free androgen index.