International Journal of Endocrinology / 2015 / Article / Tab 2

Research Article

Evidence of Insulin Resistance and Other Metabolic Alterations in Boys with Duchenne or Becker Muscular Dystrophy

Table 2

Characteristics and metabolic variables according to nutritional status in DMD/BMD patients from 4 to 18 years of agea.

UnderweightNormalOverweight/obese
( = 12)( = 39) ( = 15)

Age (years)9.2 (4.9, 17.8)8.9 (4.6, 17.1)8.5 (6.2, 15.0)
Height (mts)1.21 (0.97, 1.64)1.26 (1.0, 1.75)1.23 (1.15, 1.75)
Percentile of BMI 0.63 (0.0, 5.34)*46.37 (6.54, 81.38)93.2 (86.35, 99.74)*
Body weight (kg)19.3 (12.4, 28.1)*24.3 (14.8, 59.3)34.7 (24.7, 79.4)*
BMI (kg/m2)13.3 (10.4, 14.1)*16.0 (13.9, 22.9)21.3 (18.5, 29.5)*
Lean body mass (kg)15.44 (10.69, 22.7)16.97 (12.22, 34.07)19.24 (13.76, 34.99)*
Body fat mass (%)13.8 (7.6, 26.2)*23.6 (10.3, 57.0)39.6 (27.6, 60.0)*
Body fat mass (kg)2.6 (0.88, 5.42)*6.16 (1.58, 30.74)13.14 (8.85, 46.08)*
Glucose (mg/dL)90.08 (77.43, 104.4) 91.88 (75.67, 104.5)97.29 (75.67, 135.12)*
Insulin (U/mL)9.4 (5.2, 23.9)11.0 (5.9, 43.5) 23.7 (9.4, 59.9)*
HOMA-IR2.08 (1.04, 6.06)2.49 (1.04, 8.99)5.54 (2.21, 12.91)*
Wheelchair bound 
(number of boys)
2115

DMD/BMD: Duchene/Becker muscular dystrophy; BMI: body mass index; HOMA-IR: homeostasis model assessment-insulin resistance.
compared to normal group (ANOVA, Dunnett’s method).
aValues are median (minimum, maximum).

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