Application of Berberine on Treating Type 2 Diabetes Mellitus

Figure 3

Main mechanisms of BBR on lipid metabolism. Note: FoxO1: Forkhead transcription factor O1; ChREBP: carbohydrate responsive element-binding protein; SREBP1: sterol regulatory element-binding protein-1; LDLR mRNA: low-density lipoprotein receptor m ribonucleic acid; TG: triglyceride; CHO: cholesterol; LDL-C: low-density lipoprotein cholesterol; PPARs: peroxisome proliferator-activated receptors.