Hypothyroidism Affects Vascularization and Promotes Immune Cells Infiltration into Pancreatic Islets of Female Rabbits

Figure 1

Histological characteristics of the pancreas from control and hypothyroid female rabbits. Pictures of pancreas from control ((A) and (I)) and hypothyroid ((B)–(H) and (J)–(L)) females, showing the presence of proteoglycans ((C)–(H)) as a component of the extracellular matrix, the infiltration of immune cells ((B)–(G)), and the presence of collagen ((I)–(L)). Bar: (A)-(B) = 200 μm; (C) = 100 μm; (D), (F)–(H), (J), and (L) = 50 μm; and (E), (I), and (K) = 20 μm. ac: acinar cells; is: islets; il: interlobular septa; c: collagen; f: fat; ec: stellate cells. Black arrow: immune cells infiltration; white arrow: proteoglycans; asterisk: metaplasia.