Leptin as well as Free Leptin Receptor Is Associated with Polycystic Ovary Syndrome in Young Women
Table 2
Leptin levels (ng/mL), sOB-R (ng/mL), and LFI among PCOS subjects and in the presence/absence of overweight/obesity.
PCOS []
Control []
Leptin (ng/mL)
44.29 (16.14–47.78)
15.16 (11.87–36.27)
0.013
sOB-R (ng/mL)
14.80 (11.11–17.20)
20.06 (14.75–31.85)
0.002
FLI
2.81 (1.12–3.59)
0.86 (0.44–2.16)
0.001
BMI kg/m2
24.36 (4.88)
22.88 (4.48)
0.234
Lean (+PCOS) []
OW/OB (+PCOS) []
Leptin (ng/mL)
16.97 (10.60–45.55)
45.67 (41.98–48.04)
0.013
sOB-R (ng/mL)
16.62 (11.61–17.96)
11.47 (7.59–16.44)
0.042
FLI
1.21 (0.54–2.89)
3.33 (2.82–6.12)
0.000
Lean (+PCOS) ()
Lean (−PCOS) []
Leptin (ng/mL)
16.97 (10.60–45.55)
14.32 (10.52–24.93)
0.282
sOB-R (ng/mL)
16.62 (11.61–17.96)
23.69 (17.49–36.76)
0.002
FLI
1.21 (0.54–2.89)
0.68 (0.37–1.171)
0.041
OW/OB (+PCOS) []
OW/OB (−PCOS) []
Leptin (ng/mL)
45.67 (41.98–48.17)
39.18 (20.53–44.77)
0.029
sOB-R (ng/mL)
11.47 (7.59–16.44)
12.02 (9.09–15.26)
0.768
FLI
3.33 (2.82–6.12)
2.94 (1.88–4.43)
0.172
Data are presented by median and interquartile (IQ) values (25%–76%) and BMI as mean and SD. Data were analyzed by nonparametric Wilcoxon/Kruskal-Wallis test. Two-tailed value less than 0.05 (<0.05) is significant.
