Research Article
Gender-Specific Differences in Clinical Profile and Biochemical Parameters in Patients with Cushing’s Disease: A Single Center Experience
Table 1
Clinical features of CD by gender.
| | | Females () | Males () | value |
| | Age (years) | 33.5 (16–62) | 30.0 (14–64) | 0.762 | | BMI (kg/m2) | 24.0 (17.1–34.4) | 27.2 (20.8–35.8) | 0.076 | | Plasma K+ (mmol/L) | 4.1 (2.9–5.2) | 3.9 (3.0–4.7) | 0.310 | | Systolic blood pressure (mmHg) | 135.5 (100.0–170.0) | 152.0 (120.0–164.0) | 0.022 | | Diastolic blood pressure (mmHg) | 92.0 (62.0–129.0) | 99.5 (80.0–110.0) | 0.086 | | HbA1c (%) | 5.6 (4.7–11.0) | 5.8 (4.6–10.0) | 0.118 | | 24 h UFC (g/24 h) | 442.0 (241.2–844.4) | 671.9 (161.4–1618.2) | 0.497 | | T (nmol/L) | 1.8 (0.09–5.13) | 4.4 (1.65–12.03) | 0.001 | | Hemoglobin (g/L) | 141.0 (98.0–164.0) | 156.0 (138.0–169.0) | 0.001 | | ALT (U/L) | 26.5 (10.0–103.0) | 50.5 (20–405.0) | 0.002 | | AST (U/L) | 16.5 (10.0–34.0) | 25.5 (13.0–58.0) | 0.002 | | GGT (U/L) | 20.5 (10–112) | 60.0 (13–295) | 0.001 | | Cr (mol/L) | 54.5 (38–85) | 67.0 (56–85) | 0.000 | | CHO (mmol/L) | 5.3 (3.1–9.0) | 4.9 (3.51–7.13) | 0.952 | | TG (mmol/L) | 1.4 (0.54–4.59) | 1.7 (1.07–3.83) | 0.095 | | HDL (mmol/L) | 1.4 (0.83–2.72) | 1.3 (0.96–1.84) | 0.667 | | LDL (mmol/L) | 3.3 (1.62–6.02) | 3.4 (1.6–4.8) | 0.786 |
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Data are expressed as median and range. T, testosterone; ALT, alanine transaminase; AST, aspartate transaminase; GGT, gamma-glutamyl transaminase; CHO, cholesterol; TG, triglyceride; HDL, high-density lipoprotein; LDL, low-density lipoprotein; Mann-Whitney test.
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