The Lipid Parameters and Lipoprotein(a) Excess in Hashimoto Thyroiditis
Table 1
Demographic and laboratory results of the groups.
Overt hypothyroid
Subclinical hypothyroid
Euthyroid Hashimoto
Control
Age (mean ± SD)
35.79 ± 7.28
36.80 ± 8.19
36.30 ± 8.11
35.42 ± 7.64
0.46
TSH (mIU/mL)
11.6 [IQR: 7.27–26.2]
7.25 [IQR: 5.94–8.61]
2.39 [IQR: 1.66–3.13]
1.88 [IQR: 1.46–2.5]
<0.0001
FT3 (ng/dL)
2.09 ± 0.37
2.99 ± 0.36
3.19 ± 0.2
3.32 ± 0.43
<0.0001
FT4 (ng/dL)
0.82 [IQR: 0.69–0.89]
1.08 [IQR: 1.02–1.18]
1.17 [IQR: 1.07–1.23]
1.20 [IQR: 1.13–1.34]
<0.0001
Total-C (mg/dL)
228.16 ± 38.91
204.5 ± 40.9
183.6 ± 31.5
176.4 ± 13.6
<0.0001
TG (mg/dL)
138 [IQR: 110–160]
115 [IQR: 82.7–133.2]
98.5 [IQR: 76.7–140.7]
81.50 [IQR: 69.7–110]
<0.0001
HDL-C (mg/dL)
57.10 ± 13.73
56.34 ± 12.06
56.69 ± 11.66
54.68 ± 10.96
0.274
LDL-C (mg/dL)
144.5 [IQR: 120–166]
134 [IQR: 110–143]
116 [IQR: 102–136.7]
108.5 [IQR: 97.75–117]
<0.0001
Lp(a) (mg/dL)
32 [IQR: 15–50.3]
17.55 [IQR: 12.8–53.5]
17.85 [IQR: 15.5–38.20]
17.45 [IQR: 10.95–22.0]
0.003
Excess Lp(a) percent (%)
: 25 (52%)
: 21 (42%)
(28%)
: 6 (12%)
<0.0001
BMI (kg/m2)
26.64 ± 2.02
26.36 ± 2.22
25.58 ± 2.72
24.9 ± 2.52
<0.0001
HOMA
1.76 ± 0.54
1.68 ± 0.58
1.73 ± 0.55
1.59 ± 0.62
0.22
Normally distributed values are indicated as mean ± SD; nonnormaly distributed values are indicated as median and interquartile ranges. TSH: thyroid stimulating hormone, FT4: free thyroxin, Total-C: total cholesterol, TG: triglyceride, HDL: high density lipoprotein, LDL: low density lipoprotein, Lp(a): lipoprotein(a), and BMI: body mass index; HOMA for insulin resistance index. values are the differences of total Hashimoto groups and control group.
