The Clinical and Pathological Presentation of Thyroid Nodules in Children and the Comparison with Adult Population: Experience of a Single Institution

Table 4

Histological analysis of malignant tumors.

	Group 1 (age 3–20)	Group 2 (age 21–90)	Significance
All carcinomas	10	20
Medullary carcinoma	1 (10%)	1 (5%)
Follicular carcinoma	0	2 (10%)
Insular carcinoma	0	1 (5%)
Anaplastic carcinoma	0	1 (5%)
Papillary carcinoma	9 (90%)	15 (75%)
Follicular variant	7/9 (77.8%)	4/15 (26.7%)
Microcarcinoma	0/9 (0%)	4/15 (26.7%)
T4 tumor	7/9 (77.8%)	5/15 (33.3%)
N1a or N1b tumor	8/9 (88.9%)	10/15 (66.7%)

T4 tumor means a tumor of any size extending beyond the thyroid capsule to invade subcutaneous soft tissues, larynx, trachea, esophagus, or recurrent laryngeal nerve.
N1a metastases to level VI (pretracheal, paratracheal, and prelaryngeal lymph nodes).
N1b metastases to unilateral, bilateral, or contralateral cervical (level I, II, III, IV, or V) or retropharyngeal or superior mediastinal lymph nodes (level VII).