Research Article

FGF21 Is Associated with Acanthosis Nigricans in Obese Patients

Table 2

Correlation analysis of FGF21 in whole cohort ().

VariablesCorrelation index

BMI0.4390.000
CRP0.4920.000
UA−0.4050.001
TC0.3050.018
TG0.4580.000
Blood glucose
 (OGTT: 0 min)0.3330.009
 (OGTT: 30 min)0.3240.011
 (OGTT: 60 min)0.5030.000
 (OGTT: 120 min)0.3720.003
 (OGTT: 180 min)0.2070.113
Plasma insulin
 (OGTT: 0 min)0.6270.000
 (OGTT: 30 min)0.1580.227
 (OGTT: 60 min)0.4330.001
 (OGTT: 120 min)0.3900.002
 (OGTT: 180 min)0.4060.001
HOMA-IR0.6150.000
Percentage of body fat0.4820.000
Basal metabolic rate0.5310.000

Correlation of serum FGF21 level in all subjects. FGF21 level was positively correlated with BMI and not affected by gender. Besides, serum FGF21 levels were correlated with CRP, UA, TC, TG, blood glucose (0 min, 30 min, 1 h, and 2 h), insulin (0 min, 1 h, 2 h, and 3 h), percentage of body fat, body age, and basal metabolic rate.