Upregulation of TSHR, TTF-1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen

Figure 1

Western blot assay for the expressions of TSHR, TTF-1, and PAX8 protein in nodular goiter and the control; β-actin is also detected as an internal control. The expressions of TSHR, TTF-1, and PAX8 in nodular goiter are significantly higher than those in the control. (a, b). The iodine content (μg/mg) in nodular goiter was significantly lower than those in control tissues. (c). ; .

(a)

(b)

(c)