Upregulation of TSHR, TTF-1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen

Figure 2

Immunohistochemical analysis of the expressions and localization of TSHR, TTF-1, and PAX8 in nodular goiter and the control. The high expression of TSHR in nodular goiter is shown in (a), the moderate expression of TSHR in the controls is shown in (b); the upregulation of TTF-1 in nodular goiter is shown (c), and the moderate expression of TTF-1 in the controls is shown in (d). The high expression of PAX8 in nodular goiter is shown in (e), and the moderate expression of PAX8 in the controls is shown in (f).

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