International Journal of Endocrinology / 2016 / Article / Tab 1

Clinical Study

Valproic Acid, a Histone Deacetylase Inhibitor, in Combination with Paclitaxel for Anaplastic Thyroid Cancer: Results of a Multicenter Randomized Controlled Phase II/III Trial

Table 1

Patient characteristics.


Number of enrolled patients1411

 (i) Male85
 (ii) Female66

Age (years)
 (i) Median73.566
 (ii) Range62–8344–80

Disease stage
 (i) 4A11
 (ii) 4B15
 (iii) 4C125

Distant metastasis
 (i) Lymph nodes54
 (ii) Lung 72

Previous therapy
 (i) Radiotherapy67
 (ii) Chemotherapy47
 (iii) Thyroidectomy (incomplete)7 R0/R1 (1 R2)8 R0/R1 (1 R2)

R0/R1: macroscopically complete resection; R2 resection with minimal macroscopical residual tumor.

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