Challenges in the Diagnosis and Management of Growth Hormone Deficiency in India

Table 1

Various tests for diagnosis of growth hormone deficiency.

Study	GH assay	IGF-1 assay	Stimulation tests	Number of patients	Mean age (yrs)
Raghupathy [23]	—	—	LHRH (luteinizing hormone–releasing hormone), TRH (thyrotropin-releasing factor)	8	13.8
Kota et al. [24]	Solid-phase, 2-site CIA	Solid-phase, enzyme-labeled CIA	IIH, clonidine	25	8.6 ± 2.9 years
Ekbote et al. [25]	Solid-phase, 2-site CIA	Solid-phase, enzyme-labeled CIA	Clonidine, glucagon	28	8.6
Khadilkar et al. [26]	—	—	Stimulation tests (type not mentioned) or one test with typical phenotype	15	12
Menon et al. [27]	—	RIA	IIH, clonidine	20	9.43 ± 3.52 years
Bajpai et al. [28]	—	—	IIH, clonidine	96	9.9 ± 3.7 years
Garg et al. [29]	—	—	IIH, clonidine/exercise	71	10.07 ± 3.26 years
Kannan et al. [30]	RIA	—	IIH, clonidine, diazepam	30	2–14

CIA: chemiluminescent immunometric assay; IIH: insulin induced hypoglycaemia; RIA: radioimmunoassay.