Inositols in the Treatment of Insulin-Mediated Diseases

Table 1

Clinical studies in which MYO or DCI supplementation has been evaluated for the treatment of disease associated to insulin resistance.

Authors, year	Inositol isomers	Duration of treatment	Experimental models
Genazzani et al., 2008 [17]	MYO 2 gr	12 weeks	PCOS
Genazzani et al., 2012 [18]	MYO 2 gr	8 weeks	PCOS
Gerli et al., 2007 [19]	MYO 4 gr	14 weeks	PCOS
Artini et al., 2013 [20]	MYO 2 gr	12 weeks	PCOS
Iuorno et al., 2002 [21]	DCI 600 mg	6 to 8 weeks	PCOS
Laganà et al., 2015 [22]	DCI 1 gr	6 months	PCOS
Giordano et al., 2011 [23]	MYO 2 gr BID	6 months	Postmenopausal women with metabolic syndrome
Santamaria et al., 2012 [24]	MYO 2 gr BID	12 months	Postmenopausal women with metabolic syndrome
Corrado et al., 2011 [25]	MYO 4 gr	8 weeks	Pregnant women with gestational diabetes
D’Anna et al., 2013 [26]	MYO 2 gr	6 months	Pregnant women with a family history of type 2 diabetes

Note. MYO: myo-inositol; DCI: D-chiroinositol.