Association of Renal Resistive Index, Renal Pulsatility Index, Systemic Hypertension, and Albuminuria with Survival in Dogs with Pituitary-Dependent Hyperadrenocorticism
Table 1
Baseline characteristics of dogs.
Variable
Control ()
PDH ()
Age (years)
11.8 ± 2.9
12.2 ± 2.5
Body weight (kg)
6.3 ± 3.5
7.0 ± 3.8
Sex (female : male)
16 : 4
17 : 3
Heart rate (bpm)
121.2 ± 13.9
127.1 ± 20.3
Indirect SBP (mmHg)
132.8 ± 12.1
148.8 ± 13.9
Prevalence of hypertension (≥ 160 mmHg)
5% (1/20)
35% (7/20)
Serum albumin (g/dL)
3.3 ± 3.0
3.4 ± 4.0
Serum creatinine (mg/dL)
0.9 ± 0.3
0.8 ± 0.4
Microalbuminuria (UACR 0.03–0.3)
25% (5/20)
30% (6/20)
Albuminuria (UACR > 0.3)
0% (0/20)
40% (8/20)
Pre-ACTH cortisol (μg/dL)
1.8 ± 0.7
4.8 ± 3.0
Post-ACTH cortisol (μg/dL)
10.3 ± 2.1
29.3 ± 8.0
Data are presented as mean ± SD or % (). ACTH, adrenocorticotropic hormone; PDH, pituitary-dependent hyperadrenocorticism; SBP, systemic blood pressure; UACR, urine albumin to creatinine ratio. relative to control.