Research Article

Association of Renal Resistive Index, Renal Pulsatility Index, Systemic Hypertension, and Albuminuria with Survival in Dogs with Pituitary-Dependent Hyperadrenocorticism

Table 1

Baseline characteristics of dogs.

VariableControl ()PDH ()

Age (years)11.8 ± 2.912.2 ± 2.5
Body weight (kg)6.3 ± 3.57.0 ± 3.8
Sex (female : male)16 : 417 : 3
Heart rate (bpm)121.2 ± 13.9127.1 ± 20.3
Indirect SBP (mmHg)132.8 ± 12.1148.8 ± 13.9
Prevalence of hypertension (≥ 160 mmHg)5% (1/20)35% (7/20)
Serum albumin (g/dL)3.3 ± 3.03.4 ± 4.0
Serum creatinine (mg/dL)0.9 ± 0.30.8 ± 0.4
Microalbuminuria (UACR 0.03–0.3)25% (5/20)30% (6/20)
Albuminuria (UACR > 0.3)0% (0/20)40% (8/20)
Pre-ACTH cortisol (μg/dL)1.8 ± 0.74.8 ± 3.0
Post-ACTH cortisol (μg/dL)10.3 ± 2.129.3 ± 8.0

Data are presented as mean ± SD or % (). ACTH, adrenocorticotropic hormone; PDH, pituitary-dependent hyperadrenocorticism; SBP, systemic blood pressure; UACR, urine albumin to creatinine ratio.
relative to control.