Research Article

Melatonin in Epilepsy: A New Mathematical Model of Diurnal Secretion

Table 1

Clinical characteristics of epilepsy group (EG).

Epilepsy with focal seizures
Epilepsy with generalized seizures: Lennox-Gastaut syndrome 

Epilepsy duration (months)11–200 months12–194 months

Epilepsy etiologyUnknown etiology , 50%
Known etiology , 50%
(cortical dysplasia)
Unknown etiology , 50%
Known etiology , 50%

The number of antiepileptic drugs (mean)1–4 ()1–3 (

The frequency of seizures per day (mean)1–9 ()1–6 ()

The number of seizures on the day before the day of sampling (mean)1–3 ()1–3 (

The average number of seizures on the day of sampling11

The number of hours elapsed between the last seizure and the beginning of the sampling (mean)1–42 (12.5)1–42 (12.4)