Research Article
Melatonin in Epilepsy: A New Mathematical Model of Diurnal Secretion
Table 4
Spearman’s rank correlation coefficients calculated for the EG group. The statistically significant correlations (
< 0.05) are marked in bold.
| | Minimum melatonin concentration, | Melatonin release amplitude, | Phase shift of melatonin release, | Estimated duration of sleep, | Maximum melatonin concentration, |
| Age | 0.1717 | −0.2894 | 0.0966 | −0.1704 | −0.2694 | Quotient of intellectual development | −0.1046 | 0.1315 | 0.2065 | 0.1579 | 0.107 | Average number of seizures per day | −0.1871 | 0.3863 | 0.3171 | 0.2454 | 0.36 | The number of seizures on the day before the day of sampling | −0.1287 | 0.2736 | 0.3655 | 0.1898 | 0.2719 | The number of seizures on the day of sampling | −0.1463 | 0.244 | 0.4306 | 0.1619 | 0.238 | Number of antiepileptic drugs | −0.0731 | 0.0142 | 0.2922 | −0.1203 | 0.0121 | Epilepsy duration | −0.00427 | −0.3608 | 0.1393 | −0.1569 | −0.3468 | Hours elapsed between the last seizure and the beginning of sampling | 0.02774 | −0.33 | −0.5012 | −0.1668 | −0.3293 |
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