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International Journal of Endocrinology
Volume 2016, Article ID 4513051, 11 pages
Research Article

Ghrelin Protects against Dexamethasone-Induced INS-1 Cell Apoptosis via ERK and p38MAPK Signaling

1Hepatobiliary Surgery Department and Unit of Organ Transplantation, First Hospital of China Medical University, Shenyang 110001, China
2Hepatobiliary Surgery Department, Chifeng Municipal Hospital, Chifeng 024000, China
3Department of General Surgery, Fourth Hospital of China Medical University, Shenyang 110032, China

Received 26 November 2015; Revised 10 March 2016; Accepted 23 March 2016

Academic Editor: Marco Bugliani

Copyright © 2016 Chengshuo Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [6 citations]

The following is the list of published articles that have cited the current article.

  • Yuping Gu, Ya Zhao, Yuru Zhou, Yajun Xie, Pan Ju, Yaoshui Long, Jianing Liu, Dongsheng Ni, Fen Cao, Zhongshi Lyu, Zhaomin Mao, Jin Hao, Yiman Li, Qianya Wan, Quist Kanyomse, Yamin Liu, Die Ren, Yating Ning, Xiaofeng Li, Qin Zhou, and Bing Li, “Zeb1 Is a Potential Regulator of Six2 in the Proliferation, Apoptosis and Migration of Metanephric Mesenchyme Cells,” International Journal of Molecular Sciences, vol. 17, no. 8, pp. 1283, 2016. View at Publisher · View at Google Scholar
  • M. Billert, M. Skrzypski, M. Sassek, D. Szczepankiewicz, T. Wojciechowicz, S. Mergler, M.Z. Strowski, and K.W. Nowak, “TRPV4 regulates insulin mRNA expression and INS-1E cell death via ERK1/2 and NO-dependent mechanisms,” Cellular Signalling, 2017. View at Publisher · View at Google Scholar
  • Xin Chen, and Shanxiang Jiang, “Maduramicin-activated protein phosphatase 2A results in extracellular signal-regulated kinase 1/2 inhibition, leading to cytotoxicity in myocardial H9c2 cells,” Toxicology Letters, 2017. View at Publisher · View at Google Scholar
  • Ramachandran Vinayagam, and Baojun Xu, “7, 8-Dihydroxycoumarin (daphnetin) protects INS-1 pancreatic β-cells against streptozotocin-induced apoptosis,” Phytomedicine, vol. 24, pp. 119–126, 2017. View at Publisher · View at Google Scholar
  • Alireza Abdanipour, Masoud Dadkhah, Mohsen Alipour, and Hadi Feizi, “Effect of Ghrelin on Caspase 3 and Bcl2 Gene Expression in H2O2 Treated Rat’s Bone Marrow Stromal Cells,” Advanced Pharmaceutical Bulletin, vol. 8, no. 3, pp. 429–435, 2018. View at Publisher · View at Google Scholar
  • Ao Jiao, Feng Li, Chengshuo Zhang, Wu Lv, Baomin Chen, and Jialin Zhang, “ Simulated Cholinergic Reinnervation of β (INS-1) Cells: Antidiabetic Utility of Heterotypic Pseudoislets Containing β Cell and Cholinergic Cell ,” International Journal of Endocrinology, vol. 2018, pp. 1–13, 2018. View at Publisher · View at Google Scholar