Baseline Body Composition in Prepubertal Short Stature Children with Severe and Moderate Growth Hormone Deficiency

Table 1

Clinical characteristics and anthropometric measurements of studied groups.

	All patients (mean ± SD); ( M : F = 40 : 21)	One-way ANOVA (least squares mean ± 95 CI)				Bonferroni test
		noGHD; ( M : F = 22 : 12)	Moderate GHD; ( M : F = 9 : 7)	Severe GHD; ( M : F = 9 : 2)	value	Post hoc analysis
Age (years)					NS	NS
Bone age (years)					NS	NS
Height (SDS)					NS	NS
MPH (SDS)					NS	NS
height SDS					NS	NS
IGF-1 (SDS)					NS	NS
IGF-1 (ng/mL)					NS	NS
BMI -score (SDS)					<0.05	versus ]; versus p < 0.05; versus p < 0.05
W/HtR					<0.01	[] versus []; versus p < 0.01; versus p < 0.05
FAT (%)					<0.01	[] versus []; versus p < 0.01; versus p < 0.05
FFM (%)					<0.01	versus ]; versus p < 0.01; versus p < 0.05
PMM (%)					<0.01	versus ]; versus p < 0.01; versus p < 0.05
TBW (%)					<0.01	versus ]; versus p < 0.05; versus p < 0.05

MPH: midparental height, BMI: body mass index, GHD: growth hormone deficiency, IGF-1: insulin-like growth factor 1, FAT: fat mass, FFM: fat free mass, PMM: predicted muscle mass, TBW: total body water, and W/HtR: waist height ratio. Significant differences are presented in bold.