International Journal of Endocrinology / 2016 / Article / Fig 1

Research Article

Disproportionately Elevated Proinsulin Levels as an Early Indicator of β-Cell Dysfunction in Nondiabetic Offspring of Chinese Diabetic Patients

Figure 1

Scatterplots of measures for distinguishing abnormal glucose metabolism (panels (a), (b), and (d)) or metabolic syndrome (panel (c)). Notes: NGT-non-FDRs, normal glucose tolerance subjects with no family history of diabetes; NGT-FDRs, the first-degree relatives of T2DM with normal glucose tolerance; pre-DM-FDRs, first-degree relatives of T2DM with prediabetes; T2DM, type 2 diabetes mellitus; MetS, metabolic syndrome; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-B, homeostasis model assessment of beta-cell function; QUICKI, quantitative insulin sensitivity check index; PI, proinsulin; SI, specific insulin; PI/SI, proinsulin-to-specific insulin ratio.
(a)
(b)
(c)
(d)

We are committed to sharing findings related to COVID-19 as quickly as possible. We will be providing unlimited waivers of publication charges for accepted research articles as well as case reports and case series related to COVID-19. Review articles are excluded from this waiver policy. Sign up here as a reviewer to help fast-track new submissions.