International Journal of Endocrinology / 2016 / Article / Fig 1

Research Article

Disproportionately Elevated Proinsulin Levels as an Early Indicator of β-Cell Dysfunction in Nondiabetic Offspring of Chinese Diabetic Patients

Figure 1

Scatterplots of measures for distinguishing abnormal glucose metabolism (panels (a), (b), and (d)) or metabolic syndrome (panel (c)). Notes: NGT-non-FDRs, normal glucose tolerance subjects with no family history of diabetes; NGT-FDRs, the first-degree relatives of T2DM with normal glucose tolerance; pre-DM-FDRs, first-degree relatives of T2DM with prediabetes; T2DM, type 2 diabetes mellitus; MetS, metabolic syndrome; HOMA-IR, homeostasis model assessment of insulin resistance; HOMA-B, homeostasis model assessment of beta-cell function; QUICKI, quantitative insulin sensitivity check index; PI, proinsulin; SI, specific insulin; PI/SI, proinsulin-to-specific insulin ratio.

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