International Journal of Endocrinology

Research Article

Thyroid Stimulating Hormone Is Increased in Hypertensive Patients with Obstructive Sleep Apnea

Table 3

Multiple linear regression analysis between serum TSH and confounders in hypertensives.


	Total subjects			Age < 35 years			35 ≤ age ≤ 60 years			Age > 60 years
		Standardized coefficient			Standardized coefficient			Standardized coefficient			Standardized coefficient

Constant	1.244	—	0.034	−1.010	—	0.343	1.771	—	0.001	7.494	—	0.160
Gender	0.016	0.009	0.839	0.251	0.200	0.180	0.048	0.030	0.549	−0.746	−0.284	0.212
Age	0.010	0.122	0.012
BMI	−0.008	−0.043	0.349	−0.012	−0.101	0.499	−0.010	−0.053	0.291	−0.006	−0.016	0.943
SBP	0.000	−0.024	0.724	−0.002	−0.088	0.659	0.000	−0.010	0.895	−0.022	−0.280	0.286
DBP	0.001	0.017	0.809	0.009	0.238	0.242	0.000	−0.003	0.972	0.004	0.035	0.906
LSaO₂	−0.007	−0.103	0.030	−0.015	−0.294	0.067	−0.008	−0.125	0.014	−0.029	−0.233	0.311

Constant	0.560	—	0.203	0.302	—	0.668	1.025	—	0.008	3.357	—	0.344
Gender	0.032	0.019	0.687	0.223	0.177	0.228	0.071	0.044	0.383	−0.598	−0.228	0.344
Age	0.010	0.124	0.010
BMI	−0.009	−0.045	0.335	−0.011	−0.090	0.542	−0.011	−0.062	0.226	0.014	0.037	0.861
SBP	−0.001	−0.025	0.716	−0.003	−0.131	0.511	0.000	−0.012	0.880	−0.025	−0.326	0.224
DBP	0.001	0.021	0.763	0.011	0.294	0.154	0.000	0.001	0.990	0.020	0.160	0.561
AHI	0.004	0.101	0.036	0.009	0.357	0.070	0.005	0.140	0.007	0.017	0.187	0.377

Constant	0.446	—	0.312	0.466	—	0.506	0.982	—	0.011	3.154	—	0.379
Gender	0.008	0.005	0.915	0.230	0.183	0.212	0.062	0.039	0.447	−0.812	−0.309	0.180
Age	0.011	0.136	0.006
BMI	−0.005	−0.027	0.571	−0.010	−0.088	0.550	−0.010	−0.053	0.305	0.040	0.105	0.636
SBP	−0.001	−0.027	0.686	−0.003	−0.127	0.523	0.000	−0.012	0.876	−0.019	−0.244	0.368
DBP	0.002	0.031	0.666	0.010	0.267	0.186	0.000	0.000	0.999	0.016	0.127	0.646
ODI₃	0.001	0.035	0.478	0.006	0.351	0.179	0.003	0.106	0.044	−0.006	−0.158	0.442

Constant	0.501	—	0.256	0.365	—	0.604	1.004	—	0.009	3.343	—	0.359
Gender	0.017	0.010	0.829	0.230	0.183	0.212	0.062	0.039	0.445	−0.812	−0.309	0.189
Age	0.010	0.131	0.007
BMI	−0.007	−0.035	0.452	−0.009	−0.080	0.587	−0.010	−0.055	0.283	0.029	0.076	0.735
SBP	−0.001	−0.027	0.691	−0.003	−0.130	0.514	0.000	−0.012	0.875	−0.021	−0.274	0.315
DBP	0.002	0.027	0.701	0.010	0.276	0.175	0.000	0.001	0.985	0.018	0.148	0.596
ODI₄	0.002	0.065	0.180	0.007	0.351	0.132	0.003	0.117	0.025	−0.003	−0.059	0.776

BMI: body mass index; SBP: systolic blood pressure; DBP: diastolic blood pressure; AHI: apnea hypopnea index; LSaO₂: lowest saturation of oxygen; ODI₃: oxygen desaturation index of 3%; ODI₄: oxygen desaturation index of 4%.