International Journal of Endocrinology

Research Article

Pharmacogenetics of Risperidone and Cardiovascular Risk in Children and Adolescents

Table 1

Frequency of clinical or laboratory abnormalities in the 120 child and adolescent users of risperidone assessed by the study.
Abnormalities (%)
Overweight32 (26.7)
Obese5 (4.2)
Diabetes mellitus 0
BP8 (6.7)
Metabolic syndrome6 (5)
Increased waist circumference20 (16.7)
HOMA-IR changes22 (18.3)
Total hypercholesterolemia32 (26.7)
Hypercholesterolemia29 (24.2)
Hypocholesterolemia40 (33.3)
Hypertriglyceridemia41 (34.2)
BP, blood pressure; HOMA-IR, homeostatic model assessment of insulin resistance.
16 (13.3%) subjects were classified as prehypertensive; 44 (36.7%) subjects were classified as being between the 75th and 90th percentiles for waist circumference.