Research Article
Adipokines and Insulin Resistance in Young Adult Survivors of Childhood Cancer
Table 2
Childhood cancer survivors’ characteristics, by gender. Data are median and quartiles (1q; 3q) or mean ± SD.
| | | Total | Females | Males | value | | | | | | | | Mean ± SD | Median (q1; q3) | Mean ± SD | Median (q1; q3) | Mean ± SD | Median (q1; q3) |
| | Age (years) | 24.11 ± 3.51 | 23.59 (21.46; 25.99) | 23.88 ± 3.99 | 23.75 (20.60; 25.95) | 24.29 ± 3.131 | 23.55 (22.05; 26.01) | 0.476 | | Time from treatment completion (years) | 11.81 ± 5.19 | 12.15 (7.35; 15.50) | 11.26 ± 4.94 | 12.15 (6.62; 14.83) | 1224 ± 5.40 | 12.00 (7.50; 16.50) | 0.420 | | Weight (kg) | 71.05 ± 14.99 | 70.00 (61.00; 80.40) | 62.72 ± 12.40 | 61.05 (54.05; 69.70) | 77.26 ± 13.78 | 77.40 (66.10; 83.70) | <0.001 | | Height (m) | 1.73 ± 0.09 | 1.72 (1.67; 1.80) | 1.66 ± 0.07 | 1.67 (1.63; 1.72) | 1.77 ± 0.07 | 1.78 (1.72; 1.82) | <0.001 | | BMI (kg/m2) | 23.68 ± 4.01 | 22.94 (20.96; 25.67) | 22.59 ± 3.73 | 21.80 (19.54; 25.07) | 24.49 ± 4.06 | 24.29 (21.74; 26.61) | 0.025 | | WHR | 0.86 ± 0.13 | 0.83 (0.79; 0.92) | 0.83 ± 0.17 | 0.80 (0.71; 0.83) | 0.88 ± 0.09 | 0.86 (0.83; 0.93) | <0.001 | | FAT (g) | 21063 ± 11367 | 17361 (12779; 27228) | 26605 ± 14112 | 23390 (17043; 36393) | 18368 ± 8772 | 15753 (12380; 24093) | 0.025 | | FAT (%) | 27.04 ± 10.28 | 26.50 (19.80; 34.20) | 35.98 ± 9.61 | 37.25 (29.48; 41.58) | 22.70 ± 7.46 | 21.20 (16.75; 28.85) | <0.001 | | Lean (g) | 50644 ± 10237 | 52163 (41666; 58885) | 38921 ± 4133 | 39487 (36211; 41669) | 56347 ± 6855 | 56244 (51934; 61920) | <0.001 | | Lean/FAT | 3.14 ± 1.76 | 2.64 (1.83; 3.86) | 1.90 ± 1.09 | 1.58 (1.16; 2.36) | 3.75 ± 1.71 | 3.53 (2.33; 4.71) | <0.001 | | Insulin (IU/mL) | 9.49 ± 15.09 | 6.39 (3.69; 10.70) | 8.37 ± 5.16 | 6.70 (4.22; 12.15) | 10.18 ± 18.78 | 6.10 (2.85; 9.80) | 0.463 | | Glucose (mmol/L) | 4.99 ± 0.84 | 4.90 (4.68; 5.30) | 4.72 ± 0.97 | 4.70 (4.43; 5.28) | 5.20 ± 0.66 | 5.00 (4.78; 5.48) | 0.009 | | HOMA-IR | 0.24 ± 0.51 | 0.14 (0.07; 0.25) | 0.17 ± 0.12 | 0.13 (0.09; 0.24) | 0.28 ± 0.65 | 0.14 (0.06; 0.25) | 0.919 | | Adiponectin (ng/mL) | 7841 ± 5381 | 5639 (4333; 9570) | 10009 ± 6367 | 8282 (5144; 13660) | 6433 ± 4136 | 4707 (4044; 8305) | 0.002 | | Adiponectin/FAT in gram | 0.43 ± 0.35 | 0.30 (0.18; 0.57) | 0.41 ± 0.35 | 0.28 (0.17; 0.57) | 0.44 ± 0.36 | 0.31 (0.18; 0.57) | 0.861 | | Leptin (pg/mL) | 10343 ± 12203 | 5579 (1866; 14725) | 13900 ± 14637 | 8215 (2304; 22965) | 8030 ± 9845 | 4570 (1829; 11983) | 0.136 | | Leptin/FAT in gram | 0.58 ± 1.01 | 0.39 (0.11; 0.72) | 0.64 ± 0.44 | 0.69 (0.24; 0.97) | 0.56 ± 1.19 | 0.33 (0.10; 0.57) | 0.064 | | Leptin/adiponectin ratio | 1.94 ± 2.86 | 0.69 (0.29; 2.46) | 2.09 ± 2.95 | 1.03 (0.27; 2.58) | 1.83 ± 2.84 | 0.64 (0.30; 2.35) | 0.798 | | Resistin (ng/mL) | 9.32 ± 3.35 | 8.85 (7.01; 11.20) | 9.94 ± 2.99 | 10.00 (7.87; 11.83) | 8.92 ± 3.55 | 8.67 (6.35; 10.63) | 0.101 |
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