Putative Key Role of Inositol Messengers in Endothelial Cells in Preeclampsia

Figure 2

Inositol phosphoglycans P-type (IPG-P), which contains D-chiro inositol, can regulate the pyruvate dehydrogenase complex (PDC) by activating pyruvate dehydrogenase phosphatase (PDP) and inhibiting pyruvate dehydrogenase kinase (PDK) in a linear and sigmoid dose-dependent manner, respectively.