Research Article

Prognostic Value of Invasion, Markers of Proliferation, and Classification of Giant Pituitary Tumors, in a Georeferred Cohort in Brazil of 50 Patients, with a Long-Term Postoperative Follow-Up

Table 4

Clinical and radiological features and therapeutic intervention.

Age and radiological aspectsTherapeutic interventions value
Only surgery (%)Surgery and medical treatment (%)Surgery and radiotherapy (%)Surgery, medical treatment, and radiotherapy (%)

Patients ()11 (22)20 (40)11 (22)8 (16)

Age (years)0.0008
Diameter (mm)0.8812
Invasion
 Parasellar0.7288
  No1 (13)3 (37)3 (37)1 (13)
  Yes10 (24)17 (40)8 (19)7 (17)
 Infrasellar0.0219
  No5 (50) 1 (10) 1 (10) 3 (30)
  Yes6 (15) 19 (48) 10 (25) 5 (12)
Extension
 Suprasellar0.1600
  No0 (0)0 (0)0 (0)1 (100)
  Yes11 (22)20 (41)11 (22)7 (14)
 3rd ventricle0.1805
  No5 (28)4 (22)4 (22)5 (28)
  Yes6 (19)16 (50)7 (22)3 (9)

Values expressed as mean ± standard deviation or frequency (%) and [Pearson residual].
Tukey test results: surgery + radiotherapy versus surgery + medical treatment () and surgery + radiotherapy versus surgery + radiotherapy + medical treatment ().
value computed using Pearson’s chi-square test.