Clinical Study
The Role of Isotretinoin Therapy for Cushing’s Disease: Results of a Prospective Study
Table 3
Effect of isotretinoin (13-cis-retinoic acid) on clinical and biochemical parameters in responsive patients.
| | Parameter | Baseline | At the end of the study | value |
| | Mean HbA1c (%) | 7.60 0.10 | 7.06 0.15 | 0.50 | | Mean fasting plasma glucose (mg/dL) | 169.33 7.23 | 123.66 5.13 | 0.01 | | Mean weight (kg) | 80.5 4.85 | 73.77 4.01 | 0.01 | | Mean waist circumference (cm) | 93.37 6.26 | 85.02 4.78 | 0.01 | | Mean systolic blood pressure (mmHg) | 152.5 23.27 | 120.0 1.63 | 0.01 | | Mean diastolic blood pressure (mmHg) | 111.25 13.14 | 83.75 4.78 | 0.01 |
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