The Role of Isotretinoin Therapy for Cushing’s Disease: Results of a Prospective Study

Table 4

Efficacy of retinoic acid (RA) and 13-cis-retinoic acid (cRA) in normalizing UFC levels in patients with Cushing’s disease (data from 2 studies).

Authors (year) [ref.]	Number of patients	Drug	Dose (mg/day)	Treatment duration (months)	Rate of UFC normalization (%)
Giraldi et al. (2012) [31]	7	RA	80	6–12	42.8
Current study	16	cRA	Range, 60–80; Median, 80	6–12	25.0
All	23	—	Range, 60–80	6–12	30.4