Table of Contents Author Guidelines Submit a Manuscript
International Journal of Endocrinology
Volume 2016, Article ID 8354745, 11 pages
http://dx.doi.org/10.1155/2016/8354745
Research Article

NADPH Oxidase Inhibitor Apocynin Attenuates PCB153-Induced Thyroid Injury in Rats

Department of General Surgery, Renmin Hospital of Wuhan University, 238 Jiefang Road, Wuhan, Hubei 430060, China

Received 28 October 2015; Accepted 11 February 2016

Academic Editor: Paul M. Yen

Copyright © 2016 Ablikim Abliz et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Golden and R. Kimbrough, “Weight of evidence evaluation of potential human cancer risks from exposure to polychlorinated biphenyls: an update based on studies published since 2003,” Critical Reviews in Toxicology, vol. 39, no. 4, pp. 299–331, 2009. View at Publisher · View at Google Scholar · View at Scopus
  2. C. L. Portigal, S. P. Cowell, M. N. Fedoruk, C. M. Butler, P. S. Rennie, and C. C. Nelson, “Polychlorinated biphenyls interfere with androgen-induced transcriptional activation and hormone binding,” Toxicology and Applied Pharmacology, vol. 179, no. 3, pp. 185–194, 2002. View at Publisher · View at Google Scholar · View at Scopus
  3. S. Knerr and D. Schrenk, “Carcinogenicity of ‘non-dioxinlike’ polychlorinated biphenyls,” Critical Reviews in Toxicology, vol. 36, no. 9, pp. 663–694, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. C. Liu, C. Wang, M. Yan, C. Quan, J. Zhou, and K. Yang, “PCB153 disrupts thyroid hormone homeostasis by affecting its biosynthesis, biotransformation, feedback regulation, and metabolism,” Hormone and Metabolic Research, vol. 44, no. 9, pp. 662–669, 2012. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Fliers, A. C. Bianco, L. Langouche, and A. Boelen, “Thyroid function in critically ill patients,” The Lancet Diabetes & Endocrinology, vol. 3, no. 10, pp. 816–825, 2015. View at Publisher · View at Google Scholar
  6. A. J. Murk, E. Rijntjes, B. J. Blaauboer et al., “Mechanism-based testing strategy using in vitro approaches for identification of thyroid hormone disrupting chemicals,” Toxicology in Vitro, vol. 27, no. 4, pp. 1320–1346, 2013. View at Publisher · View at Google Scholar · View at Scopus
  7. J. D. Lambeth, “NOX enzymes and the biology of reactive oxygen,” Nature Reviews Immunology, vol. 4, no. 3, pp. 181–189, 2004. View at Publisher · View at Google Scholar · View at Scopus
  8. W. L. Cao, X. H. Xiang, K. Chen et al., “Potential role of NADPH oxidase in pathogenesis of pancreatitis,” World Journal of Gastrointestinal Pathophysiology, vol. 5, no. 3, pp. 169–177, 2014. View at Google Scholar
  9. B. Hennig, B. D. Hammock, R. Slim, M. Toborek, V. Saraswathi, and L. W. Robertson, “PCB-induced oxidative stress in endothelial cells: modulation by nutrients,” International Journal of Hygiene and Environmental Health, vol. 205, no. 1-2, pp. 95–102, 2002. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Liang, S. Y. Wu, D. Zhang, L. Wang, K. K. Leung, and P. S. Leung, “NADPH oxidase-dependent reactive oxygen species stimulate β-cell regeneration through differentiation of endocrine progenitors in murine pancreas,” Antioxidants & Redox Signaling, 2015. View at Publisher · View at Google Scholar
  11. R. B. Ning, J. Zhu, D. J. Chai et al., “RXR agonists inhibit high glucose-induced upregulation of inflammation by suppressing activation of the NADPH oxidase-nuclear factor-κB pathway in human endothelial cells,” Genetics and Molecular Research, vol. 12, no. 4, pp. 6692–6707, 2013. View at Publisher · View at Google Scholar · View at Scopus
  12. D. P. Carvalho and C. Dupuy, “Role of the NADPH Oxidases DUOX and NOX4 in thyroid oxidative stress,” European Thyroid Journal, vol. 2, no. 3, pp. 160–167, 2013. View at Publisher · View at Google Scholar
  13. H. M. van Santen, J. E. van Dijk, H. Rodermond et al., “The effect of cervical X-irradiation on activity index of thyrocytes and plasma TSH: a pre-clinical model for radiation-induced thyroid damage,” Journal of Endocrinological Investigation, vol. 28, no. 3, pp. 261–269, 2005. View at Publisher · View at Google Scholar · View at Scopus
  14. M. O. Murphy, M. C. Petriello, S. G. Han et al., “Exercise protects against PCB-induced inflammation and associated cardiovascular risk factors,” Environmental Science and Pollution Research, 2015. View at Publisher · View at Google Scholar · View at Scopus
  15. M. C. Petriello, B. Newsome, and B. Hennig, “Influence of nutrition in PCB-induced vascular inflammation,” Environmental Science and Pollution Research, vol. 21, no. 10, pp. 6410–6418, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. S. Hayley, E. Mangano, G. Crowe, N. Li, and W. J. Bowers, “An in vivo animal study assessing long-term changes in hypothalamic cytokines following perinatal exposure to a chemical mixture based on Arctic maternal body burden,” Environmental Health: A Global Access Science Source, vol. 10, article 65, 2011. View at Publisher · View at Google Scholar · View at Scopus
  17. Z. Majkova, E. Smart, M. Toborek, and B. Hennig, “Up-regulation of endothelial monocyte chemoattractant protein-1 by coplanar PCB77 is caveolin-1-dependent,” Toxicology and Applied Pharmacology, vol. 237, no. 1, pp. 1–7, 2009. View at Publisher · View at Google Scholar · View at Scopus
  18. M. J. Grimm, R. R. Vethanayagam, N. G. Almyroudis et al., “Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice,” Journal of Immunology, vol. 190, no. 8, pp. 4175–4184, 2013. View at Publisher · View at Google Scholar · View at Scopus
  19. F. Jansen, X. Yang, B. S. Franklin et al., “High glucose condition increases NADPH oxidase activity in endothelial microparticles that promote vascular inflammation,” Cardiovascular Research, vol. 98, no. 1, pp. 94–106, 2013. View at Publisher · View at Google Scholar · View at Scopus
  20. S. X. L. Zhang, A. Khalyfa, Y. Wang et al., “Sleep fragmentation promotes NADPH oxidase 2-mediated adipose tissue inflammation leading to insulin resistance in mice,” International Journal of Obesity, vol. 38, no. 4, pp. 619–624, 2014. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Ramonaite, J. Skieceviciene, S. Juzenas et al., “Protective action of NADPH oxidase inhibitors and role of NADPH oxidase in pathogenesis of colon inflammation in mice,” World Journal of Gastroenterology, vol. 20, no. 35, pp. 12533–12541, 2014. View at Publisher · View at Google Scholar · View at Scopus
  22. S. Y. Kim, K.-A. Moon, H.-Y. Jo et al., “Anti-inflammatory effects of apocynin, an inhibitor of NADPH oxidase, in airway inflammation,” Immunology and Cell Biology, vol. 90, no. 4, pp. 441–448, 2012. View at Publisher · View at Google Scholar · View at Scopus
  23. B. Hennig, P. Meerarani, R. Slim et al., “Proinflammatory properties of coplanar PCBs: in vitro and in vivo evidence,” Toxicology and Applied Pharmacology, vol. 181, no. 3, pp. 174–183, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. D. E. Williard, E. Twait, Z. Yuan, A. B. Carter, and I. Samuel, “Nuclear factor kappa B-dependent gene transcription in cholecystokinin- and tumor necrosis factor-α-stimulated isolated acinar cells is regulated by p38 mitogen-activated protein kinase,” The American Journal of Surgery, vol. 200, no. 2, pp. 283–290, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. Y. J. Cao, Y. M. Zhang, J. P. Qi, R. Liu, H. Zhang, and L. He, “Ferulic acid inhibits H2O2-induced oxidative stress and inflammation in rat vascular smooth muscle cells via inhibition of the NADPH oxidase and NF-κB pathway,” International Immunopharmacology, vol. 28, no. 2, pp. 1018–1025, 2015. View at Publisher · View at Google Scholar
  26. H. Yao, S.-R. Yang, A. Kode et al., “Redox regulation of lung inflammation: role of NADPH oxidase and NF-κB signalling,” Biochemical Society Transactions, vol. 35, no. 5, pp. 1151–1155, 2007. View at Publisher · View at Google Scholar · View at Scopus
  27. G.-L. Mo, Y. Li, R.-H. Du, D.-Z. Dai, X.-D. Cong, and Y. Dai, “Isoproterenol induced stressful reactions in the brain are characterized by inflammation due to activation of NADPH oxidase and ER stress: attenuated by apocynin, rehmannia complex and triterpene acids,” Neurochemical Research, vol. 39, no. 4, pp. 719–730, 2014. View at Publisher · View at Google Scholar · View at Scopus