International Journal of Endocrinology / 2016 / Article / Tab 4

Research Article

Long-Term Clinical Outcomes of Invasive Giant Prolactinomas after a Mean Ten-Year Followup

Table 4

Summary of persistent hyperprolactinemia analyses by univariate and multivariate COX regression analysis.

VariableUnivariate analysisMultivariate analysis&
HR (95% CI) valueHR (95% CI) value

Age (≥25 y versus <25 y)0.082 (0.007–0.929)0.0430.082 (0.007–0.929)0.043
Gender (male versus female)0.723 (0.12–4.65)0.727
Final tumor volume (no remnant versus remnant)1.434 (0.23–8.97)0.7
Cavernous sinus invasion (bilateral versus unilateral)0.612 (0.10–3.67)0.59
Treatment strategy (BRC versus S + BRC)1.6 (0.17–15.67)0.679

Probability for stepwise: entry = 0.05 and removal = 0.1.
S + BRC: surgery + bromocriptine.

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