Lipid Profile in Adolescent Girls with Type 1 Diabetes Mellitus and Hyperandrogenemia
Table 1
Clinical characteristics of adolescent girls with type 1 diabetes mellitus with (T1DM-H) and without hyperandrogenemia (T1DM-N) and healthy, regularly menstruating girls with normal androgen level (control group).
Girls with T1DM-H ()
Girls with T1DM-N ()
Control group ()
value
Chronological age [years]
16.3 ± 1.2
15.8 ± 1.4
16.2 ± 1.2
NS
Age of menarche [years]
12.9 ± 1.2
13.3 ± 1.3
12.1 ± 1.3
NS
Gynecological age [months]
40.3 ± 18.7
30.6 ± 15.7
49.1 ± 14.4
NS
Cycle duration [days]
31.5 (28.0–36.0)
28.0 (28.0–32.0)
28.0 (28.0–32.4)
NS
BMI -score
0.7 ± 0.7
0.3 ± 0.7
0.6 ± 1.4
NS
Waist-to-hip ratio
0.79 ± 0.03
1.0 ± 1.2
0.77 ± 0.04
NS
Ferriman-Gallwey score
2.1 ± 2.4
1.3 ± 2.1
2.4 ± 2.8
NS
Mean ovarian volume [ml]
4.5 ± 1.6
5.1 ± 3.4
5.7 ± 2.8
NS
Age of T1DM diagnosis [years]
7.9 ± 3.5
8.8 ± 3.5
NS
T1DM duration [years]
8.4 ± 3.3
6.9 ± 3.5
NS
Mean HbA1c from diagnosis [%]/[mmol/mol]
7.1 (6.8–8.0)/54.4 (50.8–63.9)
6.9 (6.3–7.5)/51.9 (45.4–58.5)
NS
HbA1c at study point [%]/[mmol/mol]
7.6 (6.7–9.0)/59.0 (49.7–78.9)
6.8 (6.2–7.8)/50.8 (44.3–61.2)
NS
Daily insulin requirement for the last 12 months [U/kg/day]
