Research Article

Tetrahydro-iso-alpha Acids Antagonize Estrogen Receptor Alpha Activity in MCF-7 Breast Cancer Cells

Figure 10

Effect of THIAA on [3H]E2-ERα complexation in MCF-7 cells. MCF-7 cells were incubated during 40 minutes with 10−9 M [3H]E2 and increasing concentrations of THIAA (a) or E2 (b). Whole cell [3H]E2 binding capacity was assessed by liquid scintillation counting. Data (mean ± SD) refer to a representative experiment performed three times in triplicate.
(a)
(b)