Research Article

Tetrahydro-iso-alpha Acids Antagonize Estrogen Receptor Alpha Activity in MCF-7 Breast Cancer Cells

Figure 4

Effect of THIAA on E2-stimulated MCF-7 cell proliferation in steroid-free culture medium. MCF-7 cells were grown during 72 h in the absence (control) or presence of E2 at 10−9 M with or without THIAA at indicated concentrations. Cell proliferation was measured by crystal violet staining. Data refer to the mean value ± SD of a representative experiment performed independently three times in sixplicate.