Associations of Salivary BPIFA1 Protein in Chronic Periodontitis Patients with Type 2 Diabetes Mellitus
Table 4
Salivary BPIFA1 (μg/mL, median (IQR)), TNF-α, and IL-6 (pg/mL, median (IQR)) concentrations according to age, gender, fasting blood glucose, and BMI.
BPIFA1 (median (IQR))
TNF-α (median (IQR))
IL-6 (median (IQR))
NDM
T2DM
NDM
T2DM
NDM
T2DM
Nonelderly (<60)
629.15 (1540.31–265.34)
236.28 (1316.11–103.48)
210.60 (293.03–67.12)
157.56 (455.64–58.23)
8.20 (14.00–3.21)
11.40 (28.02–2.61)
Elderly (≥60)
727.16 (1780.33–167.20)
280.79 (588.73–144.02)
67.16 (558.48–25.84)
110.35 (390.03–68.20)
7.84 (13.80–5.35)
12.22 (33.57–4.52)
value
a
a
a
a
a
a
Males
607.65 (1488.18–261.78)
285.94 (1010.52–101.88)
253.77 (463.93–62.68)
116.44 (328.92–49.38)
5.47 (15.27–2.30)
11.40 (33.57–2.95)
Females
669.97 (2016.03–243.15)
226.88 (423.01–103.47)
97.17 (241.18–37.73)
264.34 (759.63–110.35)
9.44 (13.11–5.94)
13.91 (23.43–4.20)
value
a
a
a
a
a
a
Normal fasting blood glucose (<6.1 mg/dL)
630.17 (1600.61–243.77)
415.49 (2317.82–110.59)
158.68 (269.21–44.5)
127.74 (595.21–62.86)
8.11 (13.48–4.67)
4.27 (37.84–1.63)
Elevated fasting blood glucose (≥6.1 mg/dL)
939.59 (1503.59–375.59)
253.84 (875.29–100.94)
621.17 (988.54–253.79)
151.31 (393.48–60.22)
8.31 (14.77–1.84)
12.54 (29.81–4.43)
value
a
a
a
a
a
a
Nonobese (BMI ≤ 28)
644.57 (1635.69–348.47)
285.94 (892.04–103.61)
189.70 (296.21–44.5)
145.12 (361.77–59.25)
8.75 (13.75–4.67)
10.00 (29.21–2.95)
Obese (BMI > 28)
405.00 (765.98–99.65)
201.29 (1598.02–82.00)
146.09 (733.95–46.26)
211.64 (1190.07–58.23)
6.41 (13.33–3.14)
12.86 (72.09–1140)
value
a
a
a
a
a
a
T2DM: type 2 diabetes mellitus; NDM: nondiabetes mellitus; BPIFA1: BPI fold containing family A, member 1; TNF-α: tumor necrosis factor-α; IL-6: interleukin-6; BMI: body mass index; IQR: interquartile range. P1: comparison of NDM; P2: comparison of T2DM. aIndependent sample t-test.
