Research Article
Correlation between Insulin Resistance and Thyroid Nodule in Type 2 Diabetes Mellitus
Table 1
Clinical, laboratory, and thyroid ultrasonography characteristics of study subjects (
).
| Variables | Thyroid nodule group () | Control group () | or χ2 values | values |
| Male (n (%)) | 102 (50.7) | 224 (72.7) | 25.521 | <0.001 | Age (years) | 59.13 ± 10.23 | 52.3 ± 11.23 | 6.930 | <0.001 | BMI (kg/m2) | 26.69 ± 3.64 | 26.60 ± 3.96 | 0.245 | 0.806 | WC (cm) | 95.81 ± 8.13 | 96.01 ± 8.41 | −2.66 | 0.790 | FBG (mmol/L) | 8.63 ± 3.09 | 8.26 ± 1.96 | 1.661 | 0.097 | HbA1C (%) | 9.04 ± 2.04 | 9.33 ± 2.13 | −1.576 | 0.116 | ALT (IU/L) | 21.80 ± 12.42 | 24.14 ± 16.34 | −1.73 | 0.084 | AST (IU/L) | 18.59 ± 7.18 | 19.65 ± 9.59 | −1.346 | 0.179 | BUN (mmol/L) | 5.45 ± 1.73 | 5.27 ± 1.61 | 1.251 | 0.212 | Scr (μmol/L) | 63.86 ± 21.42 | 62.30 ± 15.77 | 0.947 | 0.344 | UA (μmol/L) | 291.61 ± 81.94 | 294.26 ± 93.46 | −0.328 | 0.743 | TG (mmol/L) | 2.17 ± 3.06 | 2.09 ± 2.07 | 0.378 | 0.706 | TC (mmol/L) | 4.82 ± 1.33 | 4.66 ± 1.19 | 1.424 | 0.155 | FINS (mIU/L) | 18.22 ± 9.39 | 13.95 ± 11.40 | 4.425 | <0.001 | HOMA-IR | 8.2 ± 7.65 | 6.31 ± 9.25 | 0.159 | 0.016 | TSH (μIU/mL) | 2.17 ± 1.00 | 2.08 ± 0.92 | 1.082 | 0.28 | FT3 (pmol/L) | 4.46 ± 0.53 | 4.57 ± 0.61 | −1.981 | 0.048 | FT4 (pmol/L) | 17.04 ± 2.09 | 16.59 ± 2.11 | 2.363 | 0.019 | TPOAb (IU/mL) | 8.2 ± 7.65 | 6.31 ± 9.25 | −0.8 | 0.424 | Thyroid nodule volume (mL) | 0.29 ± 0.53 | — | — | — | Thyroid nodule size (cm) | 0.82 ± 0.45 | — | — | — |
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Values are expressed as mean ± SD or n (%). BMI: body mass index; WC: waist circumference; FBG: fasting blood glucose; HbA1c: glycated hemoglobin typeA1c; ALT: alanine aminotransferase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: creatinine; UA: uric acid; TG: triglyceride; TC: total cholesterol; FINS: fasting insulin; HOMA-IR: homeostasis model assessment insulin resistance; TSH: thyroid stimulating hormone; FT4: free thyroxine; FT3: free triiodothyronine; TPO: thyroid peroxidase antibody.
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