Melatonin as an Anti-Inflammatory Agent Modulating Inflammasome Activation

Figure 3

Melatonin protective effects against the development of oral mucositis. In detail, melatonin gel may defend mitochondria and inhibit NF-κB and NLRP3 inflammasome pathways, reducing inflammation and apoptosis. From Ortiz et al. [150] (reprinted by permission—Journal of Pineal Research license number 4123021400967).