International Journal of Endocrinology

Research Article

Mediastinal Lymph Node Metastases in Thyroid Cancer: Characteristics, Predictive Factors, and Prognosis

Table 5

Predictive factors reported in previous studies.
AuthorTypeAgeCytological typeTumor sizeT stageETELymphovascular invasionReoperationCentral neck involvementLateral neck involvementBilateral cervical metastasisDistant metastasis
Woo et al. [6]PTC XXXXX√√√  
Moritani [7]PTC√      √   
Liu et al. [10]PTCX  X   XX√√
Machens and Dralle [11]PTC          √
Choi et al. [14]PTC  √  √  √  
Machens and Dralle [15]PTC√√X √    √√
Machens et al. [18]MTC    √ √  √√
Buhr et al. [23]MTC   √     √ 
Sugenoya et al. [22]DTC   √     √ 
Ducic and Oxford [16]Thyroid    √  √   
Machens et al. [20]PTC, MTC √√   √    
√ stands for the factor that was proved to have predictive value of the mediastinal lymph node metastasis in thyroid carcinoma; X stands for the factor that was proved to have no predictive value of the mediastinal lymph node metastasis in thyroid carcinoma. ETE: extrathyroidal extension.