Obese Children with Metabolic Syndrome Have 3 Times Higher Risk to Have Nonalcoholic Fatty Liver Disease Compared with Those without Metabolic Syndrome
Table 3
Characteristics of children with and without nonalcoholic fatty liver disease (NAFLD).
Variable
NL ()
NAFLD ()
value
Sex (M/F)
25/25
35/40
0.393
Age (years)
12.1 ± 1.1
12.2 ± 1.2
0.534
Obesity
25/25
35/40
0.454
BMI (kg/m2)
30 ± 3.9
33 ± 5.2
0.001
WC (cm)
87 ± 12
97 ± 11
0.001
SBP (mm/Hg) DBP (mm/Hg)
94 ± 7.3
97 ± 7.1
0.689
ALT (U/l)
22.7 ± 6.2
26 ± 8.1
0.512
AST (U/l)
21.1 ± 7.4
25 ± 8.2
0.443
Total cholesterol (mg/dl)
165 ± 27
168 ± 29
0.654
LDL (mg/dl)
104 ± 20
105 ± 21
0.887
HDL (mg/dl)
51 ± 10
42 ± 873
0.001
Non-HDL (mg/dl)
114 ± 25
141 ± 21
0.001
Triglycerides (mg/dl)
134 ± 53
170 ± 30
0.001
Fasting blood glucose (mg/dl)
99.4 ± 7.2
88.8 ± 8.4
0.441
Fasting blood insulin (uU/ml)
25.2 ± 6.2
38.7 ± 8.4
0.001
HOMA-IR
6.18 ± 1.1
8.49 ± 1.1
0.001
MS (≥3 criteria)
5 (10%)
44 (58.6)
0.001
(statistically significant). WC: waist circumference; LDL: low-density lipoprotein; HDL: high-density lipoprotein; HOMA-IR: insulin resistance as assessed by homeostasis model. Data is presented as mean ± SD.
