Circulatory Immune Cells in Cushing Syndrome: Bystanders or Active Contributors to Atherometabolic Injury? A Study of Adhesion and Activation of Cell Surface Markers
Table 3
Cell surface marker phenotyping of immune cells.
Parameters
ACTH-dependent CS (n = 16)
ACTH-independent CS (n = 10)
Controls (n = 16)
value
Monocytes
CD14++CD16− classical (% MN)
32.7 ± 29.2
36.4 ± 33.8
42.2 ± 32.5
0.805
CD14++CD16−11b+ (%)
63.4 ± 37.5
86.6 ± 15.5
80.8 ± 19.6
0.195
CD14++CD16+ intermediate (% MN)
37.6 ± 25.1
34.2 ± 27.0
28.7 ± 26.2
0.748
CD14++CD16+11b+ (%)
47.7 ± 43.7
59.8 ± 49.1
48.1 ± 48.7
0.845
CD14+CD16++ Nonclassical (% MN)
4.9 ± 1.9
8.9 ± 3.5
5.8 ± 3.8
0.019
CD14+CD16++11b+ (%)
29.1 ± 38.7
52.9 ± 48.0
35.4 ± 41.1
0.608
Neutrophils
CD15+ (% N)
65.5 ± 27.5
66.3 ± 21.2
47.1 ± 13.9
0.205
CD15+CD16+ (%)
64.4 ± 28.0
70.2 ± 21.6
44.3 ± 12.7
0.103
CD15+CD16+ 11b (%)
74.2 ± 30.7
90.5 ± 15.3
69.2 ± 29.1
0.313
CD16+11b (% N)
85.9 ± 28.8
96.4 ± 1.5
94.2 ± 4.2
0.495
Lymphocytes
CD3+CD8+ (% L)
27.9 ± 14.1
33.2 ± 8.0
26.8 ± 8.1
0.496
CD3+CD4+ (%L)
43.6 ± 21.6
53.4 ± 12.6
54.2 ± 6.6
0.300
CD3+CD4+CD25+ (%)
18.7 ± 16.7
23.7 ± 22.7
22.7 ± 11.1
0.813
NK (% L)
30.8 ± 31.8
40.3 ± 34.4
18.4 ± 18.5
0.359
NK CD11b+ (%)
26.4 ± 31.2
47.6 ± 40.9
37.5 ± 44.4
0.541
Data are expressed as % ± standard deviation. MN: monocytes; N: neutrophils; L: lymphocytes. .
