Endocrine Gland-Derived Vascular Endothelial Growth Factor/Prokineticin-1 in Cancer Development and Tumor Angiogenesis

Figure 1

Normal tissues and malignant tumors where EG-VEGF was reported. No data about EG-VEGF interaction with normal and tumor stroma have been reported before, this being an unexplored field of EG-VEGF action, except angiogenesis (red big question mark). Other controversy should be elucidated regarding differences between EG-VEGF pathways in normal and pathologic angiogenesis.