Clinical Study

STK11 rs2075604 Polymorphism Is Associated with Metformin Efficacy in Chinese Type 2 Diabetes Mellitus

Table 2

Comparisons of allelic frequencies of STK11 rs2075604 polymorphisms in T2DM patients and healthy subjects.

GenotypesHealthy subjects
()
T2DM patients
()

STK11 rs2075604
 GG82 (41.0%)164 (41.1%)0.355
 GT87 (43.5%)189 (47.4%)
 TT31 (15.5%)46 (11.5%)
Alleles
 G251 (62.7%)517 (64.8%)0.488
 T149 (37.2%)281 (35.2%)
 HWE0.3260.445

Data was analyzed by chi-square (χ2) test. T2DM: type 2 diabetes mellitus; HWE: Hardy-Weinberg equilibrium.